Anti-PDCD10 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PDCD10 Polyclonal Antibody

品牌:solarbio | 货号:K006814P

英文名称 Anti-PDCD10 Polyclonal Antibody
宿主 Rabbit
别名 CCM3;TFAR15
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 25kDa
Gene ID 11235
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PDCD10
性状 液体
Public Immunogen Range Recombinant protein of human PDCD10
Subcellular Locations Cytoplasm
Swiss Prot Q9BUL8
克隆类型 Polyclonal Antibody
背景资料 This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Anti-OAS2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-OAS2 Polyclonal Antibody

品牌:solarbio | 货号:K006804P

英文名称 Anti-OAS2 Polyclonal Antibody
宿主 Rabbit
别名 p69 OAS / p71 OAS;2-5A synthase 2
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human Mouse
蛋白分子量 82kDa
Gene ID 4939
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human OAS2
性状 液体
Public Immunogen Range Recombinant protein of human OAS2
Subcellular Locations Cytoplasm
Swiss Prot P29728
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2′-specific nucleotidyl transfer reactions to synthesize 2′,5′-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Anti-TNFRSF11B Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TNFRSF11B Polyclonal Antibody

品牌:solarbio | 货号:K006807P

英文名称 Anti-TNFRSF11B Polyclonal Antibody
宿主 Rabbit
别名 OPG;TR1;OCIF
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 46kDa
Gene ID 4982
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human TNFRSF11B
性状 液体
Public Immunogen Range Recombinant protein of human TNFRSF11B
Subcellular Locations cytoplasm Nucleus
Swiss Prot O00300
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.?