Anti-BMP15 Polyclonal Antibody
品牌:solarbio | 货号:K005172P
| 英文名称 | Anti-BMP15 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GDF9B;ODG2;POF4 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 45kDa |
| Gene ID | 9210 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human BMP15 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human BMP15 |
| Subcellular Locations | Secreted |
| Swiss Prot | O95972 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. |