Anti-BMP15 Polyclonal Antibody
品牌:solarbio | 货号:K005172P
英文名称 |
Anti-BMP15 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
GDF9B;ODG2;POF4 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
45kDa |
Gene ID |
9210 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human BMP15 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human BMP15 |
Subcellular Locations |
Secreted |
Swiss Prot |
O95972 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. |