Anti-BAZ1B Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-BAZ1B Polyclonal Antibody

品牌:solarbio | 货号:K007895P

英文名称 Anti-BAZ1B Polyclonal Antibody
宿主 Rabbit
别名 WSTF;WBSCR9;WBSCR10
应用 IHC
稀释比例 IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 171kDa
Gene ID 9031
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human BAZ1B
性状 液体
Public Immunogen Range A synthetic peptide of human BAZ1B
Subcellular Locations Nucleus
Swiss Prot Q9UIG0
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.?

Anti-CLDN16 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CLDN16 Polyclonal Antibody

品牌:solarbio | 货号:K007904P

英文名称 Anti-CLDN16 Polyclonal Antibody
宿主 Rabbit
别名 HOMG3;PCLN1
应用 IHC
稀释比例 IHC 1:25-100.
交叉反应 Human
蛋白分子量 34kDa
Gene ID 10686
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CLDN16
性状 液体
Public Immunogen Range A synthetic peptide of human CLDN16
Subcellular Locations Membrane
Swiss Prot Q9Y5I7
克隆类型 Polyclonal Antibody
背景资料 Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28.