Anti-LDLR Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-LDLR Polyclonal Antibody

品牌:solarbio | 货号:K106578P

英文名称 Anti-LDLR Polyclonal Antibody
宿主 Rabbit
别名 FH;FHC;LDLCQ2;LDLR
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 120kDa
Gene ID 3949
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human LDLR
性状 液体
Public Immunogen Range A synthetic peptide of human LDLR
Subcellular Locations Cell membrane Cell surface Early endosome Endomembrane system Golgi apparatus Late endosome Lysosome Membrane Single-pass type I membrane protein clathrin-coated pit
Swiss Prot P01130
克隆类型 Polyclonal Antibody
背景资料 The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.

Anti-CD47 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD47 Polyclonal Antibody

品牌:solarbio | 货号:K106571P

英文名称 Anti-CD47 Polyclonal Antibody
宿主 Rabbit
别名 IAP;MER6;OA3
应用 WB IHC
稀释比例 WB 1:3000.IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 52kDa
Gene ID 961
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CD47
性状 液体
Public Immunogen Range A synthetic peptide of human CD47
Subcellular Locations Cell membrane
Swiss Prot Q08722
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene.