Anti-MAP2K6 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MAP2K6 Polyclonal Antibody

品牌:solarbio | 货号:K003429P

英文名称 Anti-MAP2K6 Polyclonal Antibody
宿主 Rabbit
别名 MAPKK6;MEK6;MKK6;PRKMK6;SAPKK-3;SAPKK3
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:50-200.
交叉反应 Human Mouse
蛋白分子量 37kDa
Gene ID 5608
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human MAP2K6
性状 液体
Public Immunogen Range Recombinant protein of human MAP2K6
Subcellular Locations Cytoplasm Nucleus cytoskeleton
Swiss Prot P52564
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Anti-MYLK Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MYLK Polyclonal Antibody

品牌:solarbio | 货号:K005630P

英文名称 Anti-MYLK Polyclonal Antibody
宿主 Rabbit
别名 AAT7;KRP;MLCK;MLCK1;MLCK108;MLCK210;MSTP083;MYLK1;smMLCK
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 211kDa
Gene ID 4638
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human MYLK
性状 液体
Public Immunogen Range Recombinant protein of human MYLK
Subcellular Locations Cell projection Cleavage furrow Cytoplasm cytoskeleton lamellipodium
Swiss Prot Q15746
克隆类型 Polyclonal Antibody
背景资料 This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3′ region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.