Anti-Phospho-RELA-S276 Polyclonal Antibody
品牌：solarbio | 货号：K006209P
| 英文名称 | Anti-Phospho-RELA-S276 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NFKB3;p65 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:20-50. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 60kDa |
| Gene ID | 5970 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S276 of human RELA |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding S276 of human RELA |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q04206 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. |