Anti-GMFB Polyclonal Antibody
品牌:solarbio | 货号:K007246P
英文名称 |
Anti-GMFB Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
GMF |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:10-50. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
17kDa |
Gene ID |
2764 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GMFB |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GMFB |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P60983 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF-∫ being produced by the tumor cells. |