Anti-PMS2 Polyclonal Antibody
英文名称 |
Anti-PMS2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PMSL2;HNPCC4;PMS2CL |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
96kDa |
Gene ID |
5395 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human PMS2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human PMS2 |
Subcellular Locations |
Nucleus |
Swiss Prot |
P54278 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. |