Anti-CXCR2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CXCR2 Polyclonal Antibody

品牌:solarbio | 货号:K007409P

英文名称 Anti-CXCR2 Polyclonal Antibody
宿主 Rabbit
别名 CD182;IL8R2;IL8RA;IL8RB;CMKAR2;CDw128b
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human
蛋白分子量 41kDa
Gene ID 3579
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CXCR2
性状 液体
Public Immunogen Range A synthetic peptide of human CXCR2
Subcellular Locations Plasma membrane
Swiss Prot P25025
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.

Anti-RAB17 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-RAB17 Polyclonal Antibody

品牌:solarbio | 货号:K005493P

英文名称 Anti-RAB17 Polyclonal Antibody
宿主 Rabbit
别名 RAB17
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 23kDa
Gene ID 64284
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human RAB17
性状 液体
Public Immunogen Range Recombinant protein of human RAB17
Subcellular Locations Cell projection Cytoplasmic side Lipid-anchor Recycling endosome membrane dendrite
Swiss Prot Q9H0T7
克隆类型 Polyclonal Antibody
背景资料 The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).

Anti-SQSTM1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-SQSTM1 Polyclonal Antibody

品牌:solarbio | 货号:K106574P

英文名称 Anti-SQSTM1 Polyclonal Antibody
宿主 Rabbit
别名 A170;DMRV;FTDALS3;NADGP;OSIL;p60;p62;p62B;PDB3;ZIP3;A170;FTDALS3;OSIL;p60;p62;p62B;PDB3;ZIP3
应用 WB IHC
稀释比例 WB 1:2000-5000.IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 50kDa
Gene ID 8878
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human SQSTM1
性状 液体
Public Immunogen Range A synthetic peptide of human SQSTM1
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q13501
克隆类型 Polyclonal Antibody
背景资料 Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

[Echelon]PI3-K 激酶活性检测试剂盒_小分子化合物_生化试剂


英文名称 PI3-Kinase Activity AlphaScreen? Assay
货期 3-5Weeks

I 型 PI3-Kinase 活性检测试剂盒,384 孔板,可用于抑制剂筛选

磷脂酰肌醇 (phosphotidylinositol,PI) 是构成细胞膜的重要组分之一,同时在细胞内外环境信号的传递上也起着非常重要的作用。

美国Echelon提供各类磷脂酰肌醇(PIPn)及检测工具 。助力细胞膜以及细胞信号通路上的研究!

Anti-AP3B1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-AP3B1 Polyclonal Antibody

品牌:solarbio | 货号:K004945P

英文名称 Anti-AP3B1 Polyclonal Antibody
宿主 Rabbit
别名 ADTB3;ADTB3A;HPS;HPS2;PE
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 121kDa
Gene ID 8546
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human AP3B1
性状 液体
Public Immunogen Range Recombinant protein of human AP3B1
Subcellular Locations Cytoplasmic side Cytoplasmic vesicle Golgi apparatus Peripheral membrane protein clathrin-coated vesicle membrane
Swiss Prot O00203
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.