Anti-ABCG2 Polyclonal Antibody
品牌:solarbio | 货号:K004115P
英文名称 |
Anti-ABCG2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ABC15;ABCP;BCRP;BCRP1;BMDP;CD338;CDw338;EST157481;GOUT1;MRX;MXR;MXR-1;MXR1;UAQTL1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat Monkey |
蛋白分子量 |
72kDa |
Gene ID |
9429 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ABCG2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ABCG2 |
Subcellular Locations |
Cell membrane Mitochondrion membrane Multi-pass membrane protein |
Swiss Prot |
Q9UNQ0 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. |