Anti-ABCG2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ABCG2 Polyclonal Antibody

品牌:solarbio | 货号:K004115P

英文名称 Anti-ABCG2 Polyclonal Antibody
宿主 Rabbit
别名 ABC15;ABCP;BCRP;BCRP1;BMDP;CD338;CDw338;EST157481;GOUT1;MRX;MXR;MXR-1;MXR1;UAQTL1
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat Monkey
蛋白分子量 72kDa
Gene ID 9429
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ABCG2
性状 液体
Public Immunogen Range Recombinant protein of human ABCG2
Subcellular Locations Cell membrane Mitochondrion membrane Multi-pass membrane protein
Swiss Prot Q9UNQ0
克隆类型 Polyclonal Antibody
背景资料 The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.