Anti-ABCG2 Polyclonal Antibody
品牌：solarbio | 货号：K004115P
| 英文名称 | Anti-ABCG2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ABC15;ABCP;BCRP;BCRP1;BMDP;CD338;CDw338;EST157481;GOUT1;MRX;MXR;MXR-1;MXR1;UAQTL1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat Monkey |
| 蛋白分子量 | 72kDa |
| Gene ID | 9429 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ABCG2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ABCG2 |
| Subcellular Locations | Cell membrane Mitochondrion membrane Multi-pass membrane protein |
| Swiss Prot | Q9UNQ0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. |