Anti-HBA2 Polyclonal Antibody
品牌：solarbio | 货号：K005829P
| 英文名称 | Anti-HBA2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HBA-T2;HBH |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Mouse Rat |
| 蛋白分子量 | 15kDa |
| Gene ID | 3040 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HBA2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HBA2 |
| Subcellular Locations | Cytosol secreted |
| Swiss Prot | P69905 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5′- zeta – pseudozeta – mu – pseudoalpha-1 – alpha-2 – alpha-1 – theta – 3′. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5′ untranslated regions and the introns, but they differ significantly over the 3′ untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. |