Anti-PCID2 Polyclonal Antibody
品牌:solarbio | 货号:K007234P
英文名称 |
Anti-PCID2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
F10 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:20-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
46kDa |
Gene ID |
55795 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PCID2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PCID2 |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q5JVF3? |
克隆类型 |
Polyclonal Antibody |
背景资料 |
PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2. Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). |