Anti-TNF11 Polyclonal Antibody
品牌：solarbio | 货号：K106545P
| 英文名称 | Anti-TNF11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD254;hRANKL2;ODF;OPGL;OPTB2;RANKL;sOdf;TNLG6B;TRANCE |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 40kDa |
| Gene ID | 8600 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TNF11 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TNF11 |
| Subcellular Locations | Cell membrane Nucleus Extracellular matrix |
| Swiss Prot | O14788 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. |