Anti-RFC2 Polyclonal Antibody
英文名称 |
Anti-RFC2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
RFC40 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
39kDa |
Gene ID |
5982 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human RFC2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human RFC2 |
Subcellular Locations |
Nucleus |
Swiss Prot |
P35250 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. |