Anti-PUMA Polyclonal Antibody
品牌:solarbio | 货号:K107009P
英文名称 |
Anti-PUMA Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BBC3,JFY-1,JFY1,BCL2 binding component 3 |
应用 |
WB |
稀释比例 |
WB 1:5000-8000. |
交叉反应 |
Human |
蛋白分子量 |
21/14/10/26kDa |
Gene ID |
27113 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human PUMA |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human PUMA |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q9BXH1 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. |