Anti-TriMethyl-Histone H4-K20 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TriMethyl-Histone H4-K20 Polyclonal Antibody

品牌:solarbio | 货号:K003343P

英文名称 Anti-TriMethyl-Histone H4-K20 Polyclonal Antibody
宿主 Rabbit
别名 FO108;H4;H4/n;H4F2;H4FN;HIST2H4
应用 WB IHC IF IP ChIP ChIPseq
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-200. IP 1:50-200. ChIP 1:20-100. ChIPseq 1:20-100.
交叉反应 Human Mouse Rat
蛋白分子量 11kDa
Gene ID 8370
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4
性状 液体
Public Immunogen Range A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4
Subcellular Locations Chromosome Nucleus
Swiss Prot P62805
克隆类型 Polyclonal Antibody
背景资料 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.