Anti-ERBB2IP Polyclonal Antibody
品牌:solarbio | 货号:K005928P
英文名称 |
Anti-ERBB2IP Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ERBIN;ERBB2IP;HEL-S-78;LAP2; |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
158kDa |
Gene ID |
55914 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ERBB2IP |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ERBB2IP |
Subcellular Locations |
Basolateral cell membrane Cell junction Nucleus membrane hemidesmosome |
Swiss Prot |
Q96RT1 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |