Anti-AKAP5 Polyclonal Antibody
品牌：solarbio | 货号：K004580P
| 英文名称 | Anti-AKAP5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AKAP75;AKAP79;H21 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 47kDa |
| Gene ID | 9495 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AKAP5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AKAP5 |
| Subcellular Locations | Lipid-anchor Membrane |
| Swiss Prot | P24588 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. |