Anti-IL-4R Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IL-4R Polyclonal Antibody

品牌:solarbio | 货号:K106750P

英文名称 Anti-IL-4R Polyclonal Antibody
宿主 Rabbit
别名 CD124;IL4-BP;IL4RA
应用 IHC
稀释比例 IHC 1:25-100.
交叉反应 Human
蛋白分子量 90kDa
Gene ID 3566
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human IL-4R
性状 液体
Public Immunogen Range A synthetic peptide of human IL-4R
Subcellular Locations Cell membrane Secreted
Swiss Prot P24394
克隆类型 Polyclonal Antibody
背景资料 Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.