Anti-PTGER4 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PTGER4 Polyclonal Antibody

品牌:solarbio | 货号:K007427P

英文名称 Anti-PTGER4 Polyclonal Antibody
宿主 Rabbit
别名 EP4;EP4R
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human
蛋白分子量 53kDa
Gene ID 5734
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human PTGER4
性状 液体
Public Immunogen Range A synthetic peptide of human PTGER4
Subcellular Locations Plasma membrane
Swiss Prot P35408
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.