Anti-PTGER4 Polyclonal Antibody
品牌:solarbio | 货号:K007427P
英文名称 |
Anti-PTGER4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EP4;EP4R |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
53kDa |
Gene ID |
5734 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human PTGER4 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human PTGER4 |
Subcellular Locations |
Plasma membrane |
Swiss Prot |
P35408 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. |