Anti-GUCY2D Polyclonal Antibody
品牌:solarbio | 货号:K003679P
英文名称 |
Anti-GUCY2D Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CORD5;CORD6;CYGD;GUC1A4;GUC2D;LCA;LCA1;RCD2;RETGC-1;ROS-GC1;ROSGC;retGC |
应用 |
WB |
稀释比例 |
WB 1:200-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
120kDa |
Gene ID |
3000 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GUCY2D |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GUCY2D |
Subcellular Locations |
Membrane Single-pass type I membrane protein |
Swiss Prot |
Q02846 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. |