Anti-GIPR Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-GIPR Polyclonal Antibody

品牌:solarbio | 货号:K006064P

英文名称 Anti-GIPR Polyclonal Antibody
宿主 Rabbit
别名 PGQTL2
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 53kDa
Gene ID 2696
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human GIPR
性状 液体
Public Immunogen Range Recombinant protein of human GIPR
Subcellular Locations Cell membrane Multi-pass membrane protein
Swiss Prot P48546
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.