Anti-GIPR Polyclonal Antibody
品牌:solarbio | 货号:K006064P
英文名称 |
Anti-GIPR Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PGQTL2 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
53kDa |
Gene ID |
2696 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GIPR |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GIPR |
Subcellular Locations |
Cell membrane Multi-pass membrane protein |
Swiss Prot |
P48546 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. |