Anti-CAV1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CAV1 Polyclonal Antibody

品牌:solarbio | 货号:K007672P

英文名称 Anti-CAV1 Polyclonal Antibody
宿主 Rabbit
别名 CGL3;PPH3;BSCL3;VIP21;MSTP085
应用 WB IHC
稀释比例 WB 1:1000-5000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 20kDa
Gene ID 857
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CAV1
性状 液体
Public Immunogen Range A synthetic peptide of human CAV1
Subcellular Locations Cytoplasm
Swiss Prot Q03135
克隆类型 Polyclonal Antibody
背景资料 The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.