Anti-CAV1 Polyclonal Antibody
品牌：solarbio | 货号：K007672P
| 英文名称 | Anti-CAV1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CGL3;PPH3;BSCL3;VIP21;MSTP085 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 20kDa |
| Gene ID | 857 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CAV1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CAV1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q03135 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |