Anti-KIF3A Polyclonal Antibody
品牌：solarbio | 货号：K008179P
| 英文名称 | Anti-KIF3A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FLA10;KLP-20 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 80kDa |
| Gene ID | 11127 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KIF3A |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KIF3A |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9Y496 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Kinesin-like protein KIF3A?is a?protein?that in humans is encoded by the?KIF3A?gene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate. |