Anti-STAT4 Polyclonal Antibody
品牌：solarbio | 货号：K004920P
| 英文名称 | Anti-STAT4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SLEB11 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 86kDa |
| Gene ID | 6775 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human STAT4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human STAT4 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q14765 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. |