Anti-LECT1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-LECT1 Polyclonal Antibody

品牌:solarbio | 货号:K004681P

英文名称 Anti-LECT1 Polyclonal Antibody
宿主 Rabbit
别名 CNMD;LECT1;BRICD3;CHM-I;CHM1;MYETS1;
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:50-100.
交叉反应 Human Mouse
蛋白分子量 37kDa
Gene ID 11061
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human LECT1
性状 液体
Public Immunogen Range Recombinant protein of human LECT1
Subcellular Locations Endomembrane system Secreted Single-pass membrane protein extracellular matrix extracellular space
Swiss Prot O75829
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.