Anti-LECT1 Polyclonal Antibody
品牌：solarbio | 货号：K004681P
| 英文名称 | Anti-LECT1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CNMD;LECT1;BRICD3;CHM-I;CHM1;MYETS1; |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 37kDa |
| Gene ID | 11061 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human LECT1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human LECT1 |
| Subcellular Locations | Endomembrane system Secreted Single-pass membrane protein extracellular matrix extracellular space |
| Swiss Prot | O75829 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. |