Anti-CHD3 Polyclonal Antibody
品牌:solarbio | 货号:K007882P
英文名称 |
Anti-CHD3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ZFH;Mi-2a;Mi2-ALPHA |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:20-100. |
交叉反应 |
Human |
蛋白分子量 |
227kDa |
Gene ID |
1107 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CHD3 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CHD3 |
Subcellular Locations |
Nucleus Cytoplasm |
Swiss Prot |
Q12873 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |