Anti-CHD3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CHD3 Polyclonal Antibody

品牌:solarbio | 货号:K007882P

英文名称 Anti-CHD3 Polyclonal Antibody
宿主 Rabbit
别名 ZFH;Mi-2a;Mi2-ALPHA
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:20-100.
交叉反应 Human
蛋白分子量 227kDa
Gene ID 1107
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CHD3
性状 液体
Public Immunogen Range A synthetic peptide of human CHD3
Subcellular Locations Nucleus Cytoplasm
Swiss Prot Q12873
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.