Anti-NEDD4L Polyclonal Antibody
品牌:solarbio | 货号:K007120P
英文名称 |
Anti-NEDD4L Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
RSP5;NEDD4-2;NEDD4.2;hNEDD4-2 |
应用 |
IHC |
稀释比例 |
IHC 1:100-300. |
交叉反应 |
Human Mouse |
蛋白分子量 |
112kDa |
Gene ID |
23327 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human NEDD4L |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human NEDD4L |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q96PU5 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.? |