Anti-STRADB Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-STRADB Polyclonal Antibody

品牌:solarbio | 货号:K008300P

英文名称 Anti-STRADB Polyclonal Antibody
宿主 Rabbit
别名 PAPK;ILPIP;ILPIPA;ALS2CR2;CALS-21;PRO1038
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 47kDa/31kDa
Gene ID 55437
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human STRADB
性状 液体
Public Immunogen Range Recombinant protein of human STRADB
Subcellular Locations Cytoplasm
Swiss Prot Q9C0K7
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.