Anti-STRADB Polyclonal Antibody
品牌:solarbio | 货号:K008300P
英文名称 |
Anti-STRADB Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PAPK;ILPIP;ILPIPA;ALS2CR2;CALS-21;PRO1038 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
47kDa/31kDa |
Gene ID |
55437 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human STRADB |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human STRADB |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q9C0K7 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |