Anti-RUNX2 Polyclonal Antibody
品牌：solarbio | 货号：K003506P
| 英文名称 | Anti-RUNX2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AML3;CBF-alpha-1;CBFA1;CCD;CCD1;CLCD;OSF-2;OSF2;PEA2aA;PEBP2aA |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 57kDa |
| Gene ID | 860 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RUNX2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RUNX2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q13950 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. |