Anti-MSH6 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MSH6 Polyclonal Antibody

品牌:solarbio | 货号:K003624P

英文名称 Anti-MSH6 Polyclonal Antibody
宿主 Rabbit
别名 GTBP;GTMBP;HNPCC5;HSAP;p160
应用 WB IF
稀释比例 WB 1:500-1000. IF 1:50-100.
交叉反应 Human Mouse
蛋白分子量 153kDa
Gene ID 2956
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human MSH6
性状 液体
Public Immunogen Range Recombinant protein of human MSH6
Subcellular Locations Nucleus
Swiss Prot P52701
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.