Anti-MSH6 Polyclonal Antibody
品牌：solarbio | 货号：K003624P
| 英文名称 | Anti-MSH6 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GTBP;GTMBP;HNPCC5;HSAP;p160 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-1000. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 153kDa |
| Gene ID | 2956 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MSH6 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MSH6 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P52701 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. |