Anti-MAFA Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MAFA Polyclonal Antibody

品牌:solarbio | 货号:K007926P

英文名称 Anti-MAFA Polyclonal Antibody
宿主 Rabbit
别名 hMafA;RIPE3b1
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 37kDa
Gene ID 389692
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human MAFA
性状 液体
Public Immunogen Range A synthetic peptide of human MAFA
Subcellular Locations Nucleus
Swiss Prot Q8NHW3
克隆类型 Polyclonal Antibody
背景资料 Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.