Anti-MAFA Polyclonal Antibody
品牌:solarbio | 货号:K007926P
英文名称 |
Anti-MAFA Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
hMafA;RIPE3b1 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
37kDa |
Gene ID |
389692 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human MAFA |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human MAFA |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q8NHW3 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. |