Anti-ITGAV Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ITGAV Polyclonal Antibody

品牌:solarbio | 货号:K007996P

英文名称 Anti-ITGAV Polyclonal Antibody
宿主 Rabbit
别名 CD51;MSK8;VNRA;VTNR
应用 IHC
稀释比例 IHC 1:50-100.
交叉反应 Human Mouse
蛋白分子量 116/112kDa
Gene ID 3685
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human ITGAV
性状 液体
Public Immunogen Range A synthetic peptide of human ITGAV
Subcellular Locations Cytoplasm Membrane
Swiss Prot P06756
克隆类型 Polyclonal Antibody
背景资料 The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.