Anti-ITGAV Polyclonal Antibody
品牌:solarbio | 货号:K007996P
英文名称 |
Anti-ITGAV Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD51;MSK8;VNRA;VTNR |
应用 |
IHC |
稀释比例 |
IHC 1:50-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
116/112kDa |
Gene ID |
3685 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human ITGAV |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human ITGAV |
Subcellular Locations |
Cytoplasm Membrane |
Swiss Prot |
P06756 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |