Anti-ITGAV Polyclonal Antibody
品牌:solarbio | 货号:K007996P
| 英文名称 | Anti-ITGAV Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD51;MSK8;VNRA;VTNR |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 116/112kDa |
| Gene ID | 3685 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ITGAV |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ITGAV |
| Subcellular Locations | Cytoplasm Membrane |
| Swiss Prot | P06756 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |