Anti-HAS1 Polyclonal Antibody
品牌:solarbio | 货号:K007720P
英文名称 |
Anti-HAS1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HAS |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
65kDa |
Gene ID |
3036 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human HAS1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human HAS1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q92839 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. |