Anti-HAS1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-HAS1 Polyclonal Antibody

品牌:solarbio | 货号:K007720P

英文名称 Anti-HAS1 Polyclonal Antibody
宿主 Rabbit
别名 HAS
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 65kDa
Gene ID 3036
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human HAS1
性状 液体
Public Immunogen Range A synthetic peptide of human HAS1
Subcellular Locations Cytoplasm
Swiss Prot Q92839
克隆类型 Polyclonal Antibody
背景资料 Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis.