Anti-EPSTI1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-EPSTI1 Polyclonal Antibody

品牌:solarbio | 货号:K007361P

英文名称 Anti-EPSTI1 Polyclonal Antibody
宿主 Rabbit
别名 BRESI1
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:30-150.
交叉反应 Human
蛋白分子量 37kDa
Gene ID 94240
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human EPSTI1
性状 液体
Public Immunogen Range A synthetic peptide of human EPSTI1
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q96J88
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene has been shown to promote tumor invasion and metastasis in some invasive cancer cells when overexpressed. Expression of this gene has been shown to be upregulated by direct binding of the Kruppel like factor 8 protein to promoter sequences. The translated protein interacts with the amino terminal region of the valosin containing protein gene product, resulting in the nuclear translocation of the nuclear factor kappa B subunit 1 gene product, and activation of target genes. Overexpression of this gene has been observed in some breast cancers and in some individuals with systemic lupus erythematosus (SLE).