Anti-CHD3 Polyclonal Antibody
品牌：solarbio | 货号：K007882P
| 英文名称 | Anti-CHD3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ZFH;Mi-2a;Mi2-ALPHA |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:20-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 227kDa |
| Gene ID | 1107 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CHD3 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CHD3 |
| Subcellular Locations | Nucleus Cytoplasm |
| Swiss Prot | Q12873 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |