Anti-NEDD4L Polyclonal Antibody
品牌：solarbio | 货号：K007120P
| 英文名称 | Anti-NEDD4L Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RSP5;NEDD4-2;NEDD4.2;hNEDD4-2 |
| 应用 | IHC |
| 稀释比例 | IHC 1:100-300. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 112kDa |
| Gene ID | 23327 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NEDD4L |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NEDD4L |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q96PU5 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.? |