Anti-HAS1 Polyclonal Antibody
品牌：solarbio | 货号：K007720P
| 英文名称 | Anti-HAS1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HAS |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 65kDa |
| Gene ID | 3036 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human HAS1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human HAS1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q92839 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. |