Anti-ROR1 Polyclonal Antibody
| 英文名称 | Anti-ROR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NTRKR1;dJ537F10.1 |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 104/43kDa |
| Gene ID | 4919 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ROR1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ROR1 |
| Subcellular Locations | Membrane |
| Swiss Prot | Q01973 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |