Anti-EGFR Polyclonal Antibody
| 英文名称 | Anti-EGFR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ERBB;ERBB1;HER1;mENA;NISBD2;PIG61 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 120kDa |
| Gene ID | 1956 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human EGFR |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human EGFR |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P00533 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. |