Anti-HRG Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-HRG Polyclonal Antibody

英文名称 Anti-HRG Polyclonal Antibody
宿主 Rabbit
别名 HPRG;HRGP;THPH11
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-100.
交叉反应 Mouse Rat
蛋白分子量 60kDa
Gene ID 3273
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human HRG
性状 液体
Public Immunogen Range Recombinant protein of human HRG
Subcellular Locations Secreted
Swiss Prot P04196
克隆类型 Polyclonal Antibody
背景资料 This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein’s effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.