Anti-IGF2R Polyclonal Antibody
| 英文名称 | Anti-IGF2R Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MPR1;MPRI;CD222;CIMPR;M6P-R |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 274kDa |
| Gene ID | 3482 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IGF2R |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IGF2R |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P11717 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. |