Anti-UVRAG Polyclonal Antibody
英文名称 |
Anti-UVRAG Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DHTX;VPS38;p63 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
78kDa |
Gene ID |
7405 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human UVRAG |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human UVRAG |
Subcellular Locations |
Chromosome Early endosome Endoplasmic reticulum Late endosome Lysosome Midbody centromere |
Swiss Prot |
Q9P2Y5 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. |