Anti-RNF34 Polyclonal Antibody
英文名称 |
Anti-RNF34 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CARP-1;CARP1;RFI;RIF;RIFF;hRFI |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
42kDa |
Gene ID |
80196 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human RNF34 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human RNF34 |
Subcellular Locations |
Cell membrane Cytoplasm Endomembrane system Nucleus Nucleus speckle Peripheral membrane protein cytosol |
Swiss Prot |
Q969K3 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. |