Anti-CLDND1 Polyclonal Antibody
| 英文名称 | Anti-CLDND1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | C3orf4;GENX-3745 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 29kDa |
| Gene ID | 56650 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CLDND1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CLDND1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9NY35 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |