Anti-UBQLN1 Polyclonal Antibody
| 英文名称 | Anti-UBQLN1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DA41;DSK2;UBQN;XDRP1;PLIC-1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 63kDa |
| Gene ID | 29979 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human UBQLN1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human UBQLN1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9UMX0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer’s and Parkinson’s disease. Two transcript variants encoding different isoforms have been found for this gene.? |