Anti-CD46 Polyclonal Antibody
| 英文名称 | Anti-CD46 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MCP;TLX;AHUS2;MIC10;TRA2.10 |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 44kDa |
| Gene ID | 4179 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CD46 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CD46 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P15529 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. |