Anti-HAT1 Polyclonal Antibody
| 英文名称 | Anti-HAT1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | KAT1 |
| 应用 | WB IHC IF ChIP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. ChIP 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 50kDa |
| Gene ID | 8520 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HAT1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HAT1 |
| Subcellular Locations | Cytoplasm Nucleus Nucleus matrix nucleoplasm |
| Swiss Prot | O14929 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. |