Anti-OTX2 Polyclonal Antibody
| 英文名称 | Anti-OTX2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CPHD6;MCOPS5 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 32kDa |
| Gene ID | 5015 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human OTX2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human OTX2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P32243 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. |