Anti-BMI1 Polyclonal Antibody
| 英文名称 | Anti-BMI1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PCGF4;RNF51;FLVI2/BMI1 |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 37kDa |
| Gene ID | 648 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human BMI1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human BMI1 |
| Swiss Prot | P35226 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | BMI1?polycomb?ring finger?oncogene, also known as?BMI1, is a?protein?which in humans is encoded by the?BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ‘Lys-119’, rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. |